Inside Health, Radio 4 Extra, and Jeremy Bowen on Today.

A recent episode of Radio 4's Inside Health, presented by James Gallagher, reported a groundbreaking advance in the biomedical study of ME - myalgic encephalomyelitis, sometimes known as chronic fatigue syndrome. On Feedback, we've heard from listeners with ME who were encouraged by the good news but wanted more personal stories that gave a message of hope. Andrea Catherwood talks to Dr Charles Shepherd, honorary medical advisor to the ME Association, about the change in attitudes to ME.

It's also a big moment for all fans of Radio 4 Extra - it's time for another All Request Weekend. We hear from a listener who put something forward for selection, and talk to the station's Editor Richard Culver about how it all works.

And we hear from listeners reacting to the Today programme's unusual decision to air an 11 minute monologue from BBC International Editor Jeremy Bowen about the strands of history of US interventions in the Middle East and involvement of US Presidents.

Presenter: Andrea Catherwood Producer: Pauline Moore Assistant Producer: Rebecca Guthrie Executive Producer: David Prest

A Whistledown Scotland production for BBC Radio 4