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One of the limitations of cancer therapy is off-target activity, which often has devastating effects on patients’ life quality. A novel strategy pursued by Cybrexa Therapeutics uses treatments specifically targeting solid tumors by taking advantage of one of their universal biomarkers – acidity. By using cell-penetrating peptides bearing an anticancer cargo load, their platform brings the treatment directly inside tumors, leaving healthy cells alone and minimizing bystander killings.
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