
Jason predicts a "major M&A moment" in the next six months! | E2213
About this episode
Register here to join Founder University Japan's kickoff: https://luma.com/cm0x90mk
Today's show:
Google and Meta had their cases dismissed (or received a slap on the wrist)… Despite all the backlash and cynicism, AI companies continue making bank and releasing hot new products… What does it all mean?
For Jason Calacanis, the signs are pointing to a "major M&A moment," with huge opportunities for increased efficiency and consolidation among America's favorite brands and largest companies?
Who will it be? Join Jason and Alex for a round of hot speculation.
PLUS why Jason thinks Michael Burry is both right and wrong about GPU depreciation, why NOTHING is certain about these OpenAI mega-deals, Google's Nano Banana Pro can make infographics and they're VERY impressive… and much more.
Timestamps:
(1:54) Jason's calling in from Vegas… He's doing a hot lap at F1!
(3:18) How restaurants are becoming the new Hot IP
(6:50) Founder University is heading to TOKYO!
(9:27) Why Jason thinks the future of startups is truly global
(10:06) Pipedrive - Bring your entire sales process into one elegant space. Get started with a 30 day free trial at pipedrive.com/twist
(11:39) Nvidia killed it on the numbers… but what are the vibes around AI? Jason sounds off.
(13:05) Why nothing is certain when it comes to the Nvidia/OpenAI deal
(19:40) Is Google now WINNING consumer adoption of AI? How did it get this close?
(19:57) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.
(26:07) Meanwhile, AI apps are still dominating the iOS Store
(27:09) Why Jason and Alex think Michael Burry's both right and wrong about GPU depreciation
(30:13) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!
(37:46) We're testing out Nano Banana Pro on a BBQ infographic challenge
(43:42) What a week for AI models! It doesn't seem like things are slowing down…
(46:12) Kalshi is growing fast, but can it catch Polymarket?
(47:50) Is a rate cut coming? Jason and Alex read the tea leaves.
(50:13) Why Jason predicts a "major M&A moment" in the next six months
(52:09) VIEWER QUESTION: What should a software engineer be working on RIGHT NOW.
(54:02) Founder Friday is now… STARTUP SUPPER CLUB
Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com
Check out the TWIST500: https://www.twist500.com
Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp
Follow Lon:
Follow Alex:
LinkedIn: https://www.linkedin.com/in/alexwilhelm
Follow Jason:
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
Thank you to our partners:
(10:06) Pipedrive - Bring your entire sales process into one elegant space. Get started with a 30 day free trial at pipedrive.com/twist
(19:57) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.
(30:13) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
Check out Jason's suite of newsletters: https://substack.com/@calacanis
Follow TWiST:
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
Instagram: https://www.instagram.com/thisweekinstartups
TikTok: https://www.tiktok.com/@thisweekinstartups
Substack: https://twistartups.substack.com
Get every episode summarized
Each time This Week in Startups publishes, we email you a written briefing from the transcript — the topics, who appeared, and any specific claims, with the ad reads skipped.
Email me new episodesFree for 3 shows. No card needed.
Hosts & guests
No transcript yet
This episode has not been transcribed. Request it and it moves to the front of the queue.
More episodes
More from This Week in Startups

Dr. Mark Hyman on Function Health & GLP-1 microdosing | E2334
This Week in Startups

Becki DeGraw on spinouts, IP licensing & clean exits | Wilson Sonsini Startup Le...
This Week in Startups

VC experts on why Physical AI funding is heating up | E2333
This Week in Startups
Are AI Agents forming "civilizations" or is this just a psy op? | 2332
This Week in Startups