
AI and I
Learn how the smartest people in the world are using AI to think, create, and relate. Each week I interview founders, filmmakers, writers, investors, and others about how they use AI tools like ChatGPT, Claude, and Midjourney in their work and in their lives. We screen-share through their historical chats and then experiment with AI live on the show. Join us to discover how AI is changing how we think about our world—and ourselves. For more essays, interviews, and experiments at the forefront of...
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Episodes (126)
MCP Servers: Teaching AI to Use the Internet Like Humans
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Cognition’s CEO on What Comes After Code
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One Developer Got Thousands of Users Before His App Launched
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Claude Code Can Be Your Second Brain
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This AI Makes a Video Game World in 40 Milliseconds
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Best of the Pod: How to Prepare for AGI According to Reid Hoffman
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Best of the Pod: She Built an AI Product Manager Bringing in Six Figures—As A Si...
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Best of the Pod: Vercel's Guillermo Rauch on AI and the Future of Coding
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Best of the Pod: Dwarkesh Patel’s Quest to Learn Everything
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Intentional Tech: Designing AI for Human Flourishing | Alex Komoroske, Cofounder...
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Arc Had Millions of Users. Why They Left It Behind for Dia. | Josh Miller and Hu...
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How We Built Our AI Email Assistant: A Behind-the-Scenes Look at Cora
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Inside OpenAI: Coaching the People Creating AGI | Joe Hudson, Founder of The Art...
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How Two Engineers Ship Like a Team of 15 With AI Agents | Kieran Klaassen, Nitye...
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The Future of AI in Medicine: From Rules to Intuition | Awais Aftab, Psychiatris...
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GitHub CEO on the AI Coding Arms Race: One Agent, 150M+ Devs
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Kevin Scott on The Future of Programming, AI Agents, and Microsoft’s Big Bet on...
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OpenAI Launches Codex: An Autonomous Programming Agent
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The $10B Hedge Fund CEO Who’s Betting Big on AI | Will England, Walleye Capital
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Jhana Meditation Silenced Her Mind—And Changed Her View On AI | Nadia Asparouhov...
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The Next AI Wave Will Be Social, Not Solo | Sarah Tavel, Benchmark and ex-Pinter...
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How to Predict the Future With Kevin Kelly, WIRED's Cofounder
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This AI Alien Will Bring In $4 Million This Year in Revenue - Ep. 56 with Quinte...
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An Inside Look at Every’s Design Philosophy - Ep. 55 with Lucas Crespo
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Being Human in the Age of Intelligent Machines - Ep. 54 with Dr. Alan Lightman
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He’s Using AI to Optimize His Life - Ep. 53 with Jonny Miller
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I Interviewed New Jersey Governor Phil Murphy about AI - Ep. 52 with Governor Ph...
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Prompt Your Way To Personal Growth - Ep. 51 with Steve Schlafman
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How AI Startups Can Win With Better Strategy - Ep. 50 with Mike Maples
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He Built an AI Audience Simulator. It’s the Future of Customer Research. - Ep. 4...
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How Nat Eliason Made $200,000 in a Week Teaching AI - Ep. 48
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Vercel’s Guillermo Rauch on What Comes After Coding - Ep. 47
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How to Prepare for AGI According to Reid Hoffman - Ep. 46
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The Venture Capitalist Who Finds the Best AI Products—Before They Win - Ep. 45 w...
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An Inside Look at Building an Email Client in 3 Months - Ep. 44 with Kieran Klaa...
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How AI Will Change Science Forever - Ep. 43 with Alice Albrecht
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The Secret to Building Sticky AI Products - Ep. 42 with Chris Pedregal
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Do 60-Minute Coding Tasks in 60 Seconds—With AI - Ep. 41 with Steve Krouse
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How We Incubate and Launch New Products With AI - Ep. 40 with Danny Aziz, Brando...
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His GPT Wrapper Has Half a Million Users—And Keeps Growing - Ep. 39 with Vicente...
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How to Win With Prompt Engineering - Ep. 38 with Jared Zoneraich
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How Notion Cofounder Simon Last Builds AI for Millions of Users - Ep. 37 with Si...
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How Union Square Ventures Built an AI Brain for Venture Capital - Ep. 36 with Ma...
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Building AI That Builds Itself - Ep. 35 with Yohei Nakajima
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How to Use AI to Become a Learning Machine - Ep. 34 with Simon Eskildsen
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How to Supercharge Your Writing With AI Tools - Ep. 33 with Evan Armstrong
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The Browser Company Is Building a Brand That Drives Viral Growth - Ep. 32 with N...
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Building an AI Media and Software Empire - Ep. 31 with Brandon Gell
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How to Be a Smarter Reader in the Age of AI - Ep. 30 with Alex Wieckowski
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How Packy McCormick Finds His Next Big Idea - Ep. 29
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