TWiV 995: Viral origin stories

TWiV discusses genetic evidence of susceptible wildlife in SARS-CoV-2 positive samples at the Huanan Wholesale Seafood Market, polio cases in African linked to a new polio vaccine that was designed to not cause the disease, and structural conservation of hepatitis B virus capsid proteins over millions of years despite a shift from a naked to an enveloped capsid.

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Download TWiV 995 (74 MB .mp3, 123 min)
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Links for this episode

•Register for ASV 2023
•MicrobeTV Discord Server
• More evidence for SARS-CoV-2 spillover (Zenodo)
•Polio cases linked to nOPV2 (Science; GPEI statement)
•nOPV2 on TWiV 756
•Engineering OPV to prevent reversion to neurovirulence (Cell Host Microbe)
•Stability of nOPV2 in children (npj Vaccines)
•2A changes compensate for 5′-UTR disruptions (Virology)
•HBV shifts from naked to enveloped (Nat Comm)
•Letters read on TWiV 995
•Timestamps by Jolene. Thanks!

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Intro music is by Ronald Jenkees

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