TWiV 908: Clinical update with Dr. Daniel Griffin

In his weekly clinical update Dr. Griffin discusses prevalence and clinical outcomes of respiratory syncytial virus versus influenza virus in adults hospitalized with acute respiratory Illness, reconsideration of antinucleocapsid IgG antibody as a marker of SARS-CoV-2 infection postvaccination for mild COVID-19 patients, assessment of COVID-19 as the underlying cause of death among children and young people aged 0 to 19 years in the US, information for persons who are immunocompromised regarding prevention and treatment of SARS-CoV-2 Infection in the context of currently circulating Omicron sublineages, association of culturable-virus detection and household transmission of SARS-CoV-2,  effectiveness of bivalent boosters against severe Omicron infection, Covid vaccines and playing the long game, efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients hospitalized with COVID-19, and severe fatigue and persistent symptoms at three months following SARS-CoV-2 Infections during the pre-Delta, Delta, and Omicron time periods.

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Links for this episode

• Prevalence and clinical outcomes of RSV vs influenza in adults (CID)
• Reconsideration of antinucleocapsid IgG antibody as a marker of SARS-CoV-2 infection (OFID)
• Assessment of COVID-19 as the underlying cause of death among children and young people (JAMA)
• Information for persons who are immunocompromised regarding prevention and treatment of SARS-CoV-2 infection (CDC)
• Association of culturable-virus detection and household transmission of SARS-CoV-2 (JID)
• Effectiveness of bivalent boosters against severe Omicron infection (NEJM)
• Covid vaccines and playing the long game (NEJM)
• Efficacy and safety of antimicrobial stewardship prospective audit and feedback in COVID-19 patients (The Lancet) 
• Severe fatigue and persistent symptoms at three months following SARS-CoV-2 Infection (CID)
• Contribute to our ASTMH fundraiser at PWB
• Dr. Griffin's treatment guide (pdf)
• Letters read on TWiV 980
• Don't crush Paxlovid (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]