TWiV 519: Fishing for viruses in senile

The TWiVomers review a potential role for herpes simplex virus type 1 as a cause of Alzheimer's Disease, including the finding that amyloid-beta acts as an antiviral by enveloping virus particles.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

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Links for this episode

• Virology Comics on sale (Amazon)
• Clinical Trial: antiviral for AD
• HHV6 and HHV7 transcripts in AD brain (TWiV 505)
• HSV1 in AD (Front Ag Neuro)
• Taiwan cohort study on antivirals and AD (Neurother)
• HSV1 antibodies in CSF (J Med Virol)
• HSV1 induces amyloid-beta fibrillization (Neuron)
• Image credit
• Letters read on TWiV 519
• Timestamps by Jolene. Thanks!

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Brianne - Pandemic (board game)
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Vincent - State of the World's Fungi

Listener Pick

David- Bruno LaTour

Intro music is by Ronald Jenkees.

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