TWiV 1108: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles, and H51 influenza infection of birds, poultry and cows before and SARS-CoV-2 circulation, before discussing if the original monovalent SARS-CoV-2 vaccine was effective in children and adolescents, how to use words to properly describe respiratory pathogens the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic, revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, if administration of remdesivir reduces mortality, long COVID, persistence of virus infection during long COVID and it prevalence. For more information about this body of work, listen to TWiV 1088.

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Links for this episode

• Measles tracking (CDC)
• Cows, chickens and birds H5N1….oh, my (USDA)
• Evolution of circulating H5N1 (CIDRAP)
• COVID-19 national trend (CDC)
• COVID-19 deaths (CDC)
• Original monovalent mRNA vaccine effectiveness in children and adolescents (MMWR)
• Updated terminology for pathogens transmitted through the air (WHO)
• Are these really better definitions for pathogens transmitted through the air (NY Times)
• Pharmaceuticals for diseases spread through the air (Reuters)
• Older adult spring booster available (CDC)
• Advisory committee for immunization practices slides (CDC)
• Advisory committee for immunization practices spring 2024 COVID-19 boosters (CDC)
• EUA for pemgarda (FDA)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Infectious Disease Society guidelines for treatment and management (IDSociety)
• WHO vs national guidelines for COVID-19 therapeutics (BMJ)
• COVID-19 and the bay of pigs (UNC)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (IDSociety)
• Outpatient treatment with concomitant vaccine-boosted convalescent plasma (mBio)
• Updated respiratory virus guidances (CDC)
• What do when your heathcare provider is infected with SARS-CoV-2 (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Remdesivir associated with reduced mortality of hospitalized oxygenated patients (OFID)
• Long COVID evidence based review TWiV shout out (TWiV 1088)
• Long COVID prevalence among adults (MMWR)
• Persistence of SARS-CoV-2 infection (Lancet Infectious Diseases)
• More questions, new answers long COVID (Lancet Infectious Diseases)
• Contribute to our ASTMH fundraiser at PWB
• Letters read on TWiV 1108
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]