TWiV 1098: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin deep dives into recent domestic and global measles and mpox outbreaks, before reviewing recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2, discussing revised guidelines for how to treat respiratory viral infection guidelines by the CDC, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, how much oxygen is necessary for effective treatment of severe disease, how COVID-19 effects the cardiovascular system of children and adolescents with long COVID and how iron metabolism may be altered during long COVID.

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Links for this episode

• Measles tracking (CDC)
• Measles in Cook County (MMWR)
• Gaps in measles vaccination drives viral surges (Infectious Disease Advisor)
• Misinformation impacts public health? Seriously? (ID Society)
• CDC alert for global and domestic measles cases and outbreaks (CDC)
• Mpox in Kamituga associated with outbreak in DRB (Eurosurviellance)
• Mpox in US, 2023 (MMWR)
• Mpox in DRC, 2024 (reliefweb)
• CDC guidance for respiratory diseases, COVID antiviral & emergence of clade I mpox (ID Society)
• ~5% of infected dead from mpox (CIDRAP)
• First cases of mpox in Republic of Congo (AP News)
• Respiratory  disease surveillance (CDC)
• RSV surveillance  (CDC)
• RSV national trend (CDC)
• Influenza/flu surveillance  (CDC)
• Influenza/flu map (CDC)
• COVID-19  hospital admissions (CDC)
• COVID-19 national trend (CDC)
• COVID-19 wastewater testing (biobot)
• Variant tracker (CDC)
• Variant hospital admissions (CDC)
• Multisystem inflammatory syndrome in children 2023 (MMWR)
• Guidance for COVID-19 in children and adolescents (JPIDS)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Molnupiravir safety and efficacy (JMV)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• What do when your heathcare provider is infected with SARS-CoV-2 (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• High/low oxygenation target (JAMA)
• How much oxygen is needed (JAMA)
• Orthostatic intolerance in long COVID and healthy volunteers (JMV)
• Autonomic cardiac function in children and adolescents with long COVID (European Journal of Pediatrics)
• Long COVID iron dysregulation and inflammatory stress erythropoiesis (Nat Imm)
• Contribute to our ASTMH fundraiser at PWB
• Letters read on TWiV 1098
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]