TWiV 1057: CMV-based HIV vaccine with Klaus Früh

Klaus Früh visits the Incubator to discuss his career and his work on cytomegalovirus-vectored vaccines which are unique in their ability to persistently maintain an immune shield of effector memory T cells, including highly unconventional MHC-II and MHC-E restricted CD8+ T cells.

Host: Vincent Racaniello, Rich Condit, and Brianne Barker

Guest: Klaus Früh

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Links for this episode

• MicrobeTV Discord Server
• MicrobeTV store at Cafepress
• Spike shirts at vaccinated.us (promo code Microbetv)
• Research assistant position in Rosenfeld Lab CBER/FDA (pdf)
• HCMV-based attenuated vaccine platform (Sci Rep)
• HLA-E-restricted, Gag-specific CD8+ T cells suppress HIV-1 infection (Sci Immunol)
• RhCMV/SIV vaccine shows long-term efficacy against SIV challenge (Sci Transl Med)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

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