TWiV 1054: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin discusses high Influenza incidence and disease severity among children and adolescents aged <18 years, neurologic effects of SARS-CoV-2 transmitted among dogs, effectiveness of monovalent mRNA vaccines against Omicron XBB infection in Singaporean children younger than 5 years, the effectiveness of COVID-19 vaccine in the prevention of post-COVID conditions, incidence and impact of acute pericarditis in hospitalized patients with COVID‐19, serotonin reduction in post-acute sequelae of viral infection, prevalence and risk factors for long COVID and post-COVID-19 condition in Africa, safety profile and clinical and virological outcomes of nirmatrelvir-ritonavir treatment in patients with advanced chronic kidney disease and COVID-19, antiviral efficacy of molnupiravir vs ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19.

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Links for this episode

• High Influenza incidence and disease severity among children and adolescents aged <18 years (CDC)
• Neurologic effects of SARS-CoV-2 transmitted among dogs (EID)
• Effectiveness of mRNA vaccines against Omicron XBB infection in Singaporean children (JAMA)
• Effectiveness of COVID-19 vaccine in the prevention of post-COVID conditions (ASHE)
• Incidence and impact of acute pericarditis in hospitalized patients with COVID‐19 (JAHA)
• Serotonin reduction in post-acute sequelae of viral infection (Cell)
• Prevalence and risk factors for long COVID and post-COVID-19 in Africa (The Lancet)
• Safety profile and clinical and virological outcomes of nirmatrelvir-ritonavir treatment in patients with kidney disease and COVID-19 (CID)
• Antiviral efficacy of molnupiravir vs ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19
• Contribute to our Floating Doctors fundraiser at PWB
• Letters read on TWiV 1054
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]