TWiV 1050: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin discusses the effectiveness of maternal mRNA COVID-19 vaccination during pregnancy against COVID-19–associated hospitalizations in infants aged <6 months during SARS-CoV-2 Omicron predominance, COVID-19 vaccination recommendations and practices for women of reproductive age by health care providers, molnupiravir for intra-household prevention of COVID-19, delayed peak SARS-CoV-2 viral loads relative to symptom onset and implications for COVID-19 testing programs, viral kinetics of sequential SARS-CoV-2 infections, FDA authorizes updated Novavax COVID-19 vaccine formulated to better protect against currently circulating variants, antiviral efficacy of molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19, long-term cardiovascular, cerebrovascular, and other thrombotic complications in COVID-19 survivors, SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels, and the efficacy of gabapentin For post-COVID-19 olfactory dysfunction.

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Links for this episode

• Effectiveness of maternal mRNA COVID-19 vaccination during pregnancy against COVID-19–associated hospitalizations in infants (CDC)
• COVID-19 vaccination recommendations and practices for women of reproductive age (CDC)
• Molnupiravir for intra-household prevention of COVID-19 (JOI)
• Delayed peak SARS-CoV-2 viral loads relative to symptom onset and implications for COVID-19 testing programs
• Viral kinetics of sequential SARS-CoV-2 infections (Nature)
• FDA authorizes updated Novavax COVID-19 vaccine (FDA)
• Antiviral efficacy of molnupiravir vs ritonavir/nirmatrelvir in patients with COVID-19 (The Lancet)
• Long-term cardiovascular, cerebrovascular, and other thrombotic complications in COVID-19 survivors (CID)
• SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in coronary vessels (NCR)
• Efficacy of gabapentin For Post–COVID-19
• Contribute to our Floating Doctors fundraiser at PWB
• Letters read on TWiV 1050
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]