
About this episode
Surgical clearance, NICM assessment, dueling perspectives on PCI as first-line therapy for angina, GDMT in HFrEF are the topics John Mandrola, MD, discusses in this week's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I. New ACC Peri-operative Guidelines Released
- ACC Guideline document https://www.jacc.org/doi/10.1016/j.jacc.2024.06.013
- J Vasc Surg https://www.jvascsurg.org/article/S0741-5214(21)00335-9/fulltext
- McFalls and colleagues; CARP https://www.nejm.org/doi/full/10.1056/NEJMoa041905
II. NICM – We may be doing it wrong in Selecting ICDs
- JAMA Meta-analysis https://jamanetwork.com/journals/jama/fullarticle/2823869/
- German CMR ICD Trial https://www.clinicaltrials.gov/study/NCT04558723
- BRITISH CMR trial https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/britishusing-cmr-scar-as-risk-indication-tool-in-nicm-and-severe-lvsd/
III. When Should PCI be Used in Chronic Stable CAD?
- Rajkumar and Al-Lamee; PCI First https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.124.011201
- Boden and De Caterina; Meds First https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.124.011268
- ORBITA 10.1016/S0140-6736(17)32714-9
- ORBITA 2 trial https://www.nejm.org/doi/full/10.1056/NEJMoa2310610
IV. GDMT Underuse in HFrEF
- Greene and colleagues https://doi.org/10.1016/j.jchf.2024.08.002
- DAPA HF https://www.nejm.org/doi/full/10.1056/NEJMoa1911303
- RALES https://www.nejm.org/doi/full/10.1056/NEJM199909023411001
You may also like:
The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington
Questions or feedback, please contact [email protected]
Get every episode summarized
Each time This Week in Cardiology publishes, we email you a written briefing from the transcript — the topics, who appeared, and any specific claims, with the ad reads skipped.
Email me new episodesFree for 3 shows. No card needed.
Hosts & guests
No transcript yet
This episode has not been transcribed. Request it and it moves to the front of the queue.
More episodes
More from This Week in Cardiology

Sep 11 2026 This Week in Cardiology
This Week in Cardiology

Sep 04 2026 This Week in Cardiology
This Week in Cardiology

Aug 28 2026 This Week in Cardiology
This Week in Cardiology

August 21 2026 This Week in Cardiology
This Week in Cardiology