
About this episode
What does the PAPA spectrum disorder teach us about SAPHO? Is SAPHO an autoinflammatory condition or part of the SpA spectrum? Why have antibiotics been used to treat this condition? Find out in this episode!
Brought to you by Tremfya.
- Intro :01
- Welcome to another exciting episode of Rheuminations :11
- About today's episode :17
- A summary of SAPHO Part 1 :24
- What to expect in this episode 1:28
- Earlier long-term data 2:27
- A more recent paper from Italy 6:47
- Therapeutics in detail 12:17
- Summary so far 21:39
- IL-1 inhibition in SAPHO 22:32
- Monogenic pediatric conditions 33:58
- Why can't we check the genes in SAPHO? 40:00
- Episode summary 41:55
- We went through a lot in this paper 45:29
- Thanks for listening 43:53
Disclosure: Brown reports no relevant financial disclosures.
We'd love to hear from you! Send your comments/questions to Dr. Brown at [email protected]. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum and be sure to check out Rheum + Boards – your destination for rheumatology education and quizzes!
References:
Agak GW, et al. J Invest Dermatol. 2014;134:366-373.
Aksentijevich I, et al. N Engl J Med. 2009;360:2426-2437.
Assmann G, Simon P. Best Pract Res Clin Rheumatol. 2011;25:423-434.
Boursier G, et al. J Invest Dermatol. 2021;141:1141-1147.
Cai R, et al. Front Cell Dev Biol. 2021;doi:10.3389/fcell.2021.643644.
Colina M, et al. Arthritis Rheum. 2009;61:813-821.
Daoussis D, et al. Semin Arthritis Rheum. 2019;48:618-625.
Eun IS, et al. J Clin Neurosci. 2021;92:153-158.
Ferguson PJ, El-Shanti H. Biomolecules. 2021;11:367.
Grosse J, et al. Blood. 2006;107:3350-3358.
Guignard S, et al. Joint Bone Spine. 2002;69:392-396.
Hayem G, et al. Semin Arthritis Rheum. 1999;29:159-171.
Holzinger D, Roth J. Curr Opin Rheumatol. 2016;28:550-559.
Hurtado-Nedelec M, et al. J Rheumatol. 2010;37:401-409.
Liao HJ, et al. Rheumatology (Oxford). 2015;54:1317-1326.
Lindor NM, et al. Mayo Clin Proc. 1997;72:611-615.
Nguyen MT, et al. Semin Arthritis Rheum. 2012;42:254-265.
Trimble BS, et al. Agents Actions. 1987;21:281-283.
Get every episode summarized
Each time Healio Rheuminations publishes, we email you a written briefing from the transcript — the topics, who appeared, and any specific claims, with the ad reads skipped.
Email me new episodesFree for 3 shows. No card needed.
Hosts & guests
No transcript yet
This episode has not been transcribed. Request it and it moves to the front of the queue.
More episodes
More from Healio Rheuminations

Healio Community Book Club: A conversation between Leonard Calabrese, DO and Kev...
Healio Rheuminations

Celebrating 101 episodes of Healio Rheuminations with Dr. Leonard Calabrese
Healio Rheuminations

The history of giant cell arteritis: Infections, injections and the man who coul...
Healio Rheuminations

The Unnecessarily Complex Story of Rheumatoid Factor
Healio Rheuminations