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newsMar 27, 20261:23

Novartis Buys Excellergy for $2B, Boosts Allergy Portfolio

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Novartis Acquires Excellergy for Up to $2B, Boosting Anti-Allergy Portfolio and U.S. Presence

Swiss pharmaceutical giant Novartis has agreed to buy California-based biotech firm Excellergy for up to $2 billion, expanding its anti-allergy offerings and strengthening its U.S. market position. The deal, set to close in H2 2026, includes an upfront cash payment and milestone payments.

Excellergys lead candidate, Exl-one eleven, targets food allergies by targeting IgE antibodies, similar to Novartiss top-selling Xolair, which treats allergic asthma and other conditions. However, Xolair now faces competition from biosimilars in European markets due to expired patents.

Early studies suggest Exl-one eleven may outperform current treatments by binding more tightly and clearing IgE faster, but larger human trials are needed to confirm these findings.

This acquisition aligns with Novartiss broader strategy, which includes a $23 billion investment over five years to develop U.S. research and manufacturing sites in states like California, Indiana, and New Jersey.

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Novartis Buys Excellergy for $2B, Boosts Allergy Portfolio

Canada News Today | 2 Min News | The Daily News Now!

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Canada News Today | 2 Min News | The Daily News Now!Novartis Buys Excellergy for $2B, Boosts Allergy Portfolio. Machine-transcribed; use the interactive transcript above to jump the player to any line.

It's March 27. From your city to your ears, this is Canada News today, powered by AI. I'm Cory with the story. Swiss drug maker Novartis is acquiring California biotech firm Excelogy in a deal worth of 2 billion dollars. This move bolsters their anti-aligee portfolio and aligns with their push into the US market. Just a week earlier, Novartis announced another big buyout, snapping up a breast cancer drug candidate from innovation therapeutics for up to 3 billion dollars. For Excelogy, they'll pay upfront cash plus milestone payments with the deals set to close in the second half of 2026, pending regulatory nods. Excelogy's lead candidate, Excel 111, targets food allergies by hitting immune system IGE antibodies, much like Novartis's top seller, Zolaire, which treats allergic asthma and more. But Zolaire now faces biosimilar rivals in European markets after some patents lapsed. Early studies show Excel 111 acts faster and stronger than current options by binding

tighter and clearing IGE quicker, the larger human. Trials are still needed to confirm that edge. This fits Novartis's broader plan, including a 23 billion dollar investment over the next five years to build US research and manufacturing sites in states like California, Indiana, New Jersey.

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