Making Vasectomy Accessible with William Prentice of Signati Medical

Vasectomy is a form of male birth control that cuts the supply of sperm to semen by cutting and sealing the tubes that carry sperm. The procedure has a low risk of problems and can usually be performed in an outpatient setting under local anesthesia. Despite contraceptive use worldwide increasing by 188 million users in the past 20 years, the number of vasectomy users fell by 27 million, a 61% decline, with almost all low-and-middle income countries reporting negligible vasectomy use. Female-to-male disparities in permanent method use have also widened further in the same period.

Joining this episode, Signati Medical’s CEO and Founder William ‘Billy’ Prentice, shares how their company is dedicated to advancing men’s health and changing the status quo. Signati plans to launch the first innovation in vasectomy in more than 20 years with a procedure that would be fast for physicians and comfortable for patients. Designed to take just minutes, this could be done right in the urologist’s office and would offer easier recovery compared to some current techniques.



From the get-go, Billy’s drive and motivation to advance the accessibility of this procedure and reduce the burden of responsibility on women, is evident. From Wall Street trader turned entrepreneur, the story of Signati and Billy’s journey is stacked with insights that are sure to leave you informed and inspired.