
Lab-Grown Food Pipes Transplanted in Pigs
About this episode
UK scientists have successfully grown and transplanted lab-grown food pipes into mini pigs, marking a significant breakthrough for children born with esophageal atresia. This innovative method, using each pigs own cells and a bioreactor, could potentially change the lives of children like Casey, who have undergone multiple surgeries due to this rare birth defect. The studys success with five out of eight pigs fully recovering within six months brings hope for human trials within five years.
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UK News Today | 2 Min News | The Daily News Now! — Lab-Grown Food Pipes Transplanted in Pigs. Machine-transcribed; use the interactive transcript above to jump the player to any line.
On March 20th, UK scientists have made a big breakthrough by growing complete food pipes in the lab and transplanting them into mini-pigs where they worked perfectly. They use small girding in mini-pigs because their size and cells closely match those of human children and built the new pipes from each pig's own. Cells on a stripped-down scaffold, grown in a special bioreactor for a week, skipping the knee for anti-rejection drugs. This could change lives for kids like two-year-old Casey, born missing 11 centimeters of his esophagus who has endured multiple surgeries to move. His stomach upward and still relies on a feeding tube while building his swallowing and speech skills. Around 18 babies a year in the UK faced this rare birth defect, and parents often juggle urgent hospital calls and two feedings as part of, everyday family life. In the study, eight pigs got the transplants, with five reaching the six-month mark fully recovered, complete with working muscles, nerves, and blood. Bessels for normal swallowing and experts at Great Orman Street Hospital now aim to test
it in children within five years.
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