
Dr. Datis Kharrazian on Mitochondria, Brain Fatigue, and Autoimmunity
About this episode
Mitochondria are the powerhouses of the cell which function to make ATP and energy. Their role in chronic disease is widely studied and often overlooked. Symptoms and root causes of mitochondrial dysfunction can be difficult to pinpoint in your patients. When it comes to relating this to brain fatigue or thyroid dysfunction, Dr. Datis Kharrazian is an expert. He has written several books and lectured extensively on these topics.
In this episode, Dr. Kharrazian outlines his approach to chronic disease using the lost art of the physical exam, laboratory assessments, and a review of current literature. Learn how he uses subtle clues to uncover root causes and what he does to improve patient outcomes.
“One of your best windows to assess mitochondrial compromise is to look at the brain.” – Dr. Datis Kharrazian
Today on The Lab Report:
- 2:40 Meet Dr. Datis Kharrazian
- 10:10 Mitochondrial dysfunction and how it affects the brain
- 13:00 Symptoms, causes, and treatment of brain fatigue
- 19:00 The functional neurological exam
- 21:00 Stimulating neurologic mitochondrial biogenesis
- 22:50 Working up brain fatigue with functional labs and physical exam
- 28:05 Functional medicine approach to autoimmune thyroid disease
- 31:32 Intestinal permeability, gluten, and lectins in autoimmunity
- 39:00 Using stool testing and food antibody testing to assess immune tolerance
- 43:40 Kharrazian explains his extensive new patient work up
- 48:35 The Kharrazian Institute
- 53:25 The Fireball
Additional Resources:
Why Do I Still Have Thyroid Symptoms When My Lab Tests Are Normal?
Subscribe, Rate, & Review The Lab Report
Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.
Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].
And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.
See omnystudio.com/listener for privacy information.
Get every episode summarized
Each time The Lab Report publishes, we email you a written briefing from the transcript — the topics, who appeared, and any specific claims, with the ad reads skipped.
Email me new episodesFree for 3 shows. No card needed.
No transcript yet
This episode has not been transcribed. Request it and it moves to the front of the queue.
More episodes
More from The Lab Report

An Open Forum with Dr. Shilpa Saxena
The Lab Report

The Other Side of the Fire with Jessica Meyers
The Lab Report

Fracture-Proof Your Future - Bone Health with Dr. John Neustadt
The Lab Report

Navigating Autism and Finding Theo's Voice with Heather Acquavella and Dr. Jared...
The Lab Report