COVID-19 Miniseries Episode 36: A Comprehensive Update on COVID-19

This episode was recorded on June 5, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest: Raymund R. Razonable, M.D. (@RazonableMD)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Up to about 50% of people infected with SARS-CoV-2 are asymptomatic spreaders. About 80% of those who are symptomatic, developing COVID-19, have mild disease displaying dry cough, fever, and fatigue. The resulting 20% of symptomatic patients accounts for those who develop progressive respiratory distress and sometimes multi-organ failure, among other complications. We’re learning more about anosmia, cardiac injury, and “COVID-toes.” What’s known about COVID-19 and SARS-CoV-2 continues to evolve. Dr. Raymund Razonable walks through a recently published update on the management of COVID-19. 

Time Stamps: 1:18 - New signs and symptoms of COVID-19. 3:30 - Testing characteristics (sensitivity, specificity, and indications)  of the molecular and serologic testing for SARS-CoV-2 6:22 - Risk factors and the prediction of disease progression for patients hospitalized with COVID-19 9:28 - Hyper-inflammatory syndrome and progression to multi-system organ failure syndrome 10:45 - Multisystem inflammatory syndrome in children (MIS-C) 11:22 - Cardiac complications - 3 factors 12:50 - Diagnosis and treatment of co-infection in hospitalized patients (COVID-19 and flu, COVID-19 and pneumonia) 16:31 - Evidence-based treatment based on the 3 phases of COVID-19 viremic phase, pneumonic phase, hyperinflammation phase 18:06 - Remdesivir update 21:00 - Hydroxychloroquine update 23:25 - Favipiravir and lopinavir-ritonavir update 23:53 - Treatment of the hyperinflammatory phase (sarilumab, tocilizumab, lenzilumab, anakinra,) 27:13 - Convalescent plasma 28:04 - Discharge and social determinants of health 33:40 - Telehealth and remote monitoring 35:40 - Health disparities and telehealth 37:47 - What’s the next development Infectious Disease specialists are looking for in relation to the COVID-19 pandemic?

See the article here: A Collaborative Multidisciplinary Approach to the Management of Coronavirus Disease-19 in the Hospital Setting https://doi.org/10.1016/j.mayocp.2020.05.010

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

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