Can Pressurized Oxygen Actually Rewire Your Depressed Brain?

In today's episode we're exploring Hyperbaric Oxygen Therapy (HBOT), a treatment originally for decompression sickness that is now showing potential for rewiring depressed brains.

Depression affects one in three people, and traditional antidepressants fail roughly 30% of patients.

We look at how HBOT works by having patients breathe pure oxygen in a pressurized chamber, which causes oxygen to dissolve into blood plasma at much higher concentrations.

This floods key brain areas with oxygen, boosting cellular function and mitigating chronic neuroinflammation, a contributor to persistent low mood.

The evidence is promising but preliminary, particularly for those with treatment-resistant depression or traumatic brain injuries.

However, HBOT courses can cost thousands of dollars, and research suggests it works best when combined with other interventions like psychotherapy or medication.

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