48. Chemical Imbalance Revisited

On July 20, 2022 a review was published in the journal of Molecular Psychiatry. This review compiled 30 years of research into serotonin and depression in full showing little evidence of any abnormality of serotonin in people with depression.

The Chemical Imbalance theory of depression has been widely publicized by Doctors and the Media for decades. This serotonin theory of depression has influenced millions to take or continue antidepressant medication.

IT IS REALLY IMPORTANT THAT YOU DO NOT STOP YOUR ANTIDEPRESSANTS SUDDENLY OR TOO FAST.

Today we discuss this review and its implications.

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If you are in a crisis or think you have an emergency, call your doctor or 911. If you're considering suicide, call 1-800-273-TALK to speak with a skilled trained counselor.

ADDITIONAL RESOURCES

Moncrieff, J., Cooper, R.E., Stockmann, T. et al. The serotonin theory of depression: a systematic umbrella review of the evidence. Mol Psychiatry (2022)

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19:00 - RollingStone: Who Is the Psychiatrist Behind the Antidepressant Study Taking Over Right-Wing Media?

33:00 - The naturalistic course of unipolar major depression in the absence of somatic therapy

36:00 - Relabeling the Medications We Call Antidepressants - PMC

45:00 - How to take the news that depression has not been shown to be caused by a chemical imbalance | Joanna Moncrieff

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