204: Programmable bacteria for antitumor immunity
About this episode
Host: Vincent Racaniello
Guests: Nicholas Arpaia and Tal Danino
Vincent meets up with Nick and Tal to explain how they engineered E. coli to lyse within tumors and deliver an antibody that causes tumor regression in mice.
Links for this episode:
- Programmable bacteria induce tumor immunity (Nat Med)
- Synchronized cycles of bacterial lysis (Nature)
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