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欢迎来到科研喵播客，这里是你的AI助力，labcat.com.cn。今天，我们带来一篇《循环研究》的最新报道，影响因子高达16.5。研究人员通过创建一种新型小鼠模型，深入探讨了高胆固醇和高血压对冠状动脉粥样硬化的影响。研究发现，小鼠模型中的ApoE(SA/SA)在西式饮食下发展出轻度冠状动脉粥样硬化和心力衰竭，而额外的Ang II诱导的高血压显著加速了冠状动脉粥样硬化的发展，导致心肌梗死。这一发现揭示了冠状动脉对Ang II的特异性易感性，为冠心病的研究和治疗提供了新的视角。科研喵，用AI读文献，祝你效率百倍。
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