The Gut Fungiome

The gut microbiome is more than just bacteria. It encompasses all organisms and genetic material including yeast, viruses, and archaea. It is a common belief that yeast in the GI tract needs to be eradicated. But not so fast.

In this episode, we focus on the mycobiome. We examine the dual roles of commensal and pathogenic yeast species within the GI tract, exploring how they influence immune signaling, metabolic function, and mucosal integrity. We also discuss emerging evidence linking fungal dysbiosis to conditions such as Inflammatory Bowel Disease, cancer, and systemic inflammation.

If you’re interested in the clinical science behind how yeast can support health – or contribute to disease - this episode explores a topic often overlooked in longevity medicine.

Today on The Lab Report:

• 4:00 The Gut Mycobiome – needs a new name
• 6:40 Yeast vs. Bacteria
• 9:00 Development of the commensal mycobiome
• 11:00 The important role of yeast & their metabolites
• 15:25 Candida and Malassezia
• 18:45 Saccharomyces
• 21:05 Dietary influences and fermented foods
• 23:30 Question of the Day
  • If yeast grows out in culture on the GI Effects, what next?

Additional Resources:

GI Effects Stool Profile

Microbiomix 

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