Dysbiosis: The Moving Target

Based on recent research, the term ‘dysbiosis’ is no longer a simple black-and-white diagnosis of a gut imbalance. The scientific understanding of a healthy microbiome is evolving. It’s no longer just about the laundry list of organisms present, but rather about their functionality for health and disease.

In today’s episode, we unpack the term ‘dysbiosis.’ Join us to rethink what it means to have a healthy microbiome, the utility of novel algorithmic scoring, and how a deeper understanding of this complex ecosystem is opening doors to more targeted diagnostics and therapeutics.  

Today on The Lab Report:

• 4:30 Healthy microbiome vs. Dysbiosis
• 8:00 Defining terms
• 10:10 Dysbiosis scoring algorithms
• 15:40 Functional approach to dysbiosis
• 16:30 Rethinking pathogens
• 19:25 The microbiome is reactionary – root cause is important!
• 23:15 Should we even be using the word “dysbiosis”?
• 24:25 Whole genome sequencing and gut functionality
• 28:00 Adaptability of the microbiome

Additional Resources:

GI Effects Stool Profile

Microbiomix

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