49ers Draft Picks: Offense & Defense

0:00It's March 23rd. This is NFL News Today, football coverage powered by AI. The San Francisco 49ers head into the 2026 NFL Draft with six elections in the first four rounds. They hold the 27th pick in the first round, the 58th in the second, and four picks in the fourth round at numbers 127, 133, 138, and 139. That comes after trading their third rounder for Dallas Cowboys defensive lineman, OSA Oda Gizua, NFL.com analyst Chad Reuter mocked out the early rounds for every team, leaning offense for the 49ers with picks that target key needs. In the first round, he has them grabbing Utah offensive tackle Caleb Lomu to bolster the line. Then in round two, Notre Dame running back to Darian Price steps in as a backup to Christian McCaffrey with starter potential down the road. Reuter loaded up on offense early, adding Mississippi Statewide receiver Brennan Thompson as a fourth option behind their top trio.

1:01Price brings strong rushing stats from the past two college seasons, topping 1,400 yards and 18 touchdowns. Thompson dominated the SEC last year with over 1,000 receiving yards and six scores. On defense, Alabama edge rusher LT Overton could plug a gap right away with nine sacks over two years. Boston college tackle Jew Bowery and Duke Cornerback Chandler Rivers round out the fourth round hall as solid depth pieces with good college tape. These choices mix immediate help with long-term building box, setting the 49ers up well despite picking late in each round.